Download e-book for iPad: The Ribonucleic Acids by P.R. Stewart, D.S. Letham

By P.R. Stewart, D.S. Letham

ISBN-10: 1461263603

ISBN-13: 9781461263609

ISBN-10: 146126362X

ISBN-13: 9781461263623

The relevant position of the ribonucleic acids (RNA) in mediating the expression of data encoded in DNA in residing cells is now good demonstrated. examine during this quarter of biology maintains at a extraordinary fee, and new and important info appears to be like virtually day-by-day in a variety of journals, released symposia and professional experiences. the various nature of this knowledge makes it tough for the newcomer to the sphere of RNA biochemistry to procure a normal view of confirmed options, present job, and new advances. furthermore, the reports to be had are usually fascinated about insular features of those Ubiquitous molecules, or in relation to textual content­ books, the topic is handled as a part of a basic define of right­ ties of nucleic acids and therefore will be superficial. The authors of the chapters during this assortment try and offer a finished, notwithstanding now not overly exact, define of the biologi­ cal roles of RNA. they've got written for college students with simple education in biochemistry, yet differently with a wide selection of organic interests-plant body structure, virology, organelle bio­ chemistry, genetics, mobilephone biology, differentiation and improvement. Viral RNA, which used to be handled as a separate bankruptcy within the first variation, has been deleted from this version since it is an unman­ ageably huge unmarried subject, and while is addressed in a couple of methods in lots of diversified locations within the book.

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DELEO, A. : Proc. Nat. Acad. Sci. S. 71, 225 (1974). : FEBS Lett. 2,57 (1968). VARMUS, H. , PERLMAN, R. : Nature New BioI. 230,41 (1971). VENIS, M. : Proc. Nat. Acad. Sci. S. 68, 1824 (1971). : Eur. J. Biochem. 3, 194 (1967). WARD, D. , GOLDBERG, I. : Science 149, 1259 (1965). WARING, M. : Biochim. Biophys. Acta. 114,234 (1966). WARING, M. : J. Mol. BioI. 54,247 (1970). , AUGUST, J. : J. Mol. BioI. 33, 21 (1968). WAYNE, P. K, ROSEN, O. : Proc. Nat. Acad. Sci. S. 71, 1436 (1974). WEAVER, R. , S.

1975). E. Control of Eukaryote Transcription Genome size and organizational complexity is in general much greater in eukaryotic cells than in prokaryotes. The transcriptional control systems must be considerably more complex in eukaryotes than in prokaryotes to account for the temporal and differential aspects of gene expression associated with differentiation in higher organisms. This section deals with some major models for eukaryote transcriptional control and some major relevant features of chromosomal organization.

J. Mol. BioI. 44, 195 (1969). CHAPTER 3 Nuclear RNA H. NAoRA Introduction The cell nucleus is the main center for the storage of genetic information and regulation of gene expression. Virtually all of the cellular DNA is now known to be nuclear. Chloroplasts and mitochondria contain their own DNA, but the amount of DNA and informational content in these organelles is small relative to the nuclear genome. The nucleus is now recognized as the major site of RNA synthesis. It contains the vast majority ofthe primary transcripts, most of which are processed and transported to the cytoplasm, although some are found only in the nucleus and never enter the cytoplasm.

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